With odds of 9/1 stacked against the Railwaymen, cartaker boss Dario Gradi will have his work cut out against top the table Leicester City.
The Railwaymen have yet to win on the road this season and will be looking for something after the 3-0 home defeat to Stockport last Saturday.
Nigel Pearsons Foxes will be looking to stay top of League One as they look to get out of League One at the first attempt. The Foxes went top on Saturday with an imressive away win to Scunthorpe United who they replaced.
Crewe Alex Team News....
Crewe cartaker boss Dario Gradi has wielded the axe and has replaced Steve Collis with Stuart Tomlinson who will make his first appearance since 2006. On loan midfielder Stuart Green is ruled out with a hamstring injury so Gradi calls upon Colin Daniel into the team.
Michael O'Connor looks set to be recalled in place of James Bailey after the Northern Ireland midfielder served a one-match ban on Saturday.
Clayton Donaldson looks set to keep his place but could be partnered by Anthony Elding as the Railwaymen go in search of goals.
Leicester City Team News.....
Nigel Pearson can call upon Steve Howard after the striker served a one-match ban but Pearson will make a late decision whether Paul Henderson (groin) and Marc Edworthy (knee) can play.