Crewe hope to do better than last season after they went out in the third round to Bolton Wanderers.
The youngsters will have to travel to Boundary Park home of Oldham Athletic in which the tie must be played before Saturday 11 November.
Doncaster Rovers v Rochdale
Grimsby Town v Huddersfield Town
Oldham Athletic v Crewe Alexandra
Macclesfield Town v Curzon Ashton or Marine
Dunston FB or York City v Leigh RMI or Bootle
Chester City v Farsley Celtic or Silsden
Accrington Stanley v Darlington
Blackpool v Hartlepool United
Bury v Tranmere Rovers
Stockport County v Rotherham United
Scunthorpe United v Bradford City
Wrexham v Carlisle United
Eccleshill United or North Ferriby Utd v Worksop Town or Morecambe
Walsham Le Willows v Rugby Town or Gornal Athletic or Great Yarmouth Town
Shrewsbury Town v Arnold Town or Leek Town
Cambridge United or Bury Town v Hednesford Town or Worcester City or Histon
Boston United v Port Vale
Coventry Sphinx or Eccleshall v Nottingham Forest
Sutton Coldfield Town v Walsall or Stafford Rangers
Mansfield Town v Northampton Town
Lincoln City v Malvern Town or Boldmere St Michaels
Kings Lynn or Lowestoft Town v Chesterfield
Hemel Hempstead Town v Dagenham & Redbridge or Fisher Athletic or Canvey Island
Gillingham v Stevenage Borough or Thamesmead Town
Harrow Borough or Staines Town v Woking or Worthing
Westfield or East Grinstead Town v Salisbury City or Beaconsfield SYCOB
North Greenford United v Tonbridge Angels or Gravesend & Northfleet or Dunstable Town
Milton Keynes Dons v Lewes or Haywards Heath Town
Leyton Orient v Winchester City or Oxford United
Barnet v Millwall
AFC Wimbledon or Chelmsford City v Chesham United or Thatcham Town
Brentford v Rushden & Diamonds or Barton Rovers
Brighton & Hove Albion v Ramsgate or Epsom & Ewell
Ashford Town (Middx) or Redbridge v Wycombe Wanderers
Swansea City v Swindon Town
Exeter City or Gloucester City v AFC Bournemouth
Yeovil Town v Aldershot Town or Oxford City
Bristol City v Cheltenham Town
Merthyr Tydfil or Bishop Sutton v Weymouth or Cirencester Town
Hereford United v Bristol Rovers